Reduction in inflammation Improvements in skin and hair health Enhancement of stress resilience
- Reduction in inflammation markers (e.g., C-reactive protein, oxidative stress markers);
- Activation of autophagy and cellular detoxification, facilitated by Ca-AKG and AMPK pathway stimulation;
- Improvements in skin and hair health, associated with enhanced collagen synthesis and reduced oxidative stress;
- Neurotransmitter regulation, leading to better mood stability and stress resilience;
- Ca-AKG has been shown to modulate inflammatory markers and enhance mitochondrial function, while NMN supports sirtuin activation, a critical longevity pathway.
Improvements in overall well-being Enhanced insulin sensitivity
- Enhanced mitochondrial biogenesis, leading to improved metabolic efficiency and cellular respiration;
- Optimized cardiovascular health, with sustained improvements in endothelial function and nitric oxide availability;
- Support for bone density and joint health, as Ca-AKG has been linked to osteoblast activation and reduced age-associated frailty;
- Studies suggest that prolonged use can enhance insulin sensitivity and support metabolic health;
- Potential reversal of epigenetic aging markers, as seen in research on methylation clocks and longevity compounds.
Increased heath-span and longevity
- Continuous cellular repair and mitochondrial efficiency, supporting long-term health span;
- Improved immune function, with evidence suggesting NAD+ supports T-cell activation and adaptive immune responses;
- Metabolic flexibility and glucose homeostasis, reducing risk factors associated with age-related metabolic decline;
- Potential for increased health span and longevity, based on preclinical and emerging human data on NAD+ precursors.
